jmc

In order to produce a multiple of 63, we must choose at least two factors of 3 and one factor of 7 among the prime factorizations of the two numbers we choose. We count the number of ways in which we can do this by considering the four multiples of 7 in our list. There are two which are not multiples of 3 (7 and 35) and two that are multiples of 3 but not 9 (21 and 42). Each of 7 and 35 can be paired with 27 to give a multiple of 63, so that's two successes. Each of 21 and 42 can be paired with any of 3, 27, or 51, which gives another $2\cdot 3=6$ successes. Finally, we can choose both 21 and 42, and we have a total of $2+6+1=9$ successes.

Since there are $\left(\genfrac{}{}{0ex}{}{7}{2}\right)=21$ total ways to choose a pair of numbers from the list, the probability that a randomly chosen pair of numbers will have a product which is a multiple of 63 is $\frac{9}{21}=\boxed{\frac{3}{7}}$.